289-Fujimoto-MitralCell thumbnail

289-Fujimoto-MitralCell

Author reviewed
Image data showing activity-dependent dendrite remodeling in the developing mouse olfactory bulb and barrel cortex
Project ID
289-Fujimoto-MitralCell
Project SID
289
Title
Image data showing activity-dependent dendrite remodeling in the developing mouse olfactory bulb and barrel cortex
Description
In developing brains, activity-dependent remodeling facilitates the formation of precise neuronal connectivity. Synaptic competition is known to facilitate synapse elimination; however, it has remained unknown how different synapses compete with one another within a post-synaptic cell. Here, the authors investigate how a mitral cell in the mouse olfactory bulb prunes all but one primary dendrite during the developmental remodeling process. They find that spontaneous activity generated within the olfactory bulb is essential. They show that strong glutamatergic inputs to one dendrite trigger branch-specific changes in RhoA activity to facilitate the pruning of the remaining dendrites: NMDAR-dependent local signals suppress RhoA to protect it from pruning; however, the subsequent neuronal depolarization induces neuron-wide activation of RhoA to prune non-protected dendrites. NMDAR-RhoA signals are also essential for the synaptic competition in the mouse barrel cortex. These results demonstrate a general principle whereby activity-dependent lateral inhibition across synapses establishes a discrete receptive field of a neuron.
Submission Date
2023-05-19
Opened Date
-
Release Date
2026-08-07
Update Date
-
Kind
Image datasets
License
Project URL
-
Project DOI
-
Metadata Version
-
Template Version
3.0.1
Funding Information
This work was supported by grants from the PRESTO and CREST (JPMJCR2021 to T.I.) programs of the Japan Science and Technology Agency (JST) (T.I.), AMED (JP20dm0207055 and JP23wm0525012 to T.I.), the JSPS KAKENHI (JP23680038, JP15H05572, JP15K14336, JP16K14568, JP16H06456, JP17H06261, JP21H00205, JP21H05696, JP23H02577, and JP23H04236 to T.I.; JP15K14327, JP17K14944, and JP19K06886 to S.F.; JP17K14946 to M.N.L.; and JP18J10215 to S.A.), Mitsubishi Foundation (T.I.), Sumitomo Foundation (T.I.), Nakajima Foundation (T.I.), the Mochida Memorial Foundation for Medical and Pharmaceutical Research, the Uehara Memorial Foundation (T.I.), and a RIKEN CDB intramural grant (T.I.). S.A. was a junior research associate at RIKEN and a predoctoral research fellow (DC2) of JSPS.
Total
27608 files / 991.3 GB
Image datasets
zipped 461 files / 240.1 GB, raw image 27147 files / 751.2 GB, total 27608 files / 991.3 GB
Quantitative datasets
zipped 0 files / 0 bytes, raw bdml 0 files / 0 bytes, total 0 files / 0 bytes

Biosample

Organism
Mus musculus ( NCBITaxon:10090 )
Strain
Cell
mitral cell ( CL:1001502 )
ciliated olfactory receptor neuron ( CL:0000847 )
neuron ( CL:0000540 )
Cell line
-
MeSH
Neurons ( D009474 )
Microscopy, Confocal ( D018613 )
Olfactory Bulb ( D009830 )
Neuronal Plasticity ( D009473 )
Cell Body ( D066146 )
Brain ( D001921 )
Dendrites ( D003712 )
Synapses ( D013569 )
Microscopy, Fluorescence, Multiphoton ( D036641 )
Calcium Signaling ( D020013 )
Time-Lapse Imaging ( D059008 )
Axons ( D001369 )
rhoA GTP-Binding Protein ( D020742 )
Fluorescence Resonance Energy Transfer ( D031541 )
rac1 GTP-Binding Protein ( D020830 )
Cerebral Cortex ( D002540 )
Cytoplasm ( D003593 )

Ontology

Anatomical Entity
-
UBERON
olfactory bulb brain ( UBERON:0000955 )
barrel cortex ( UBERON:0010415 )
cerebral cortex ( UBERON:0000956 )
brain ( UBERON:0000955 )
Biological Process
neuron development neuron remodeling ( GO:0016322 )
calcium ion transport ( GO:0006816 )
neuron development ( GO:0048666 )
negative regulation of neuron remodeling ( GO:1904800 )
postsynaptic signal transduction ( GO:0098926 )
response to odorant ( GO:1990834 )
Cellular Component
cell body ( GO:0044297 )
dendrite ( GO:0030425 )
glutamatergic synapse ( GO:0098978 )
axon ( GO:0030424 )
cytoplasm ( GO:0005737 )
presynapse ( GO:0098793 )
Molecular Function
-
Medical Subject Headings
Neurons ( D009474 )
Microscopy, Confocal ( D018613 )
Olfactory Bulb ( D009830 )
Neuronal Plasticity ( D009473 )
Cell Body ( D066146 )
Brain ( D001921 )
Dendrites ( D003712 )
Synapses ( D013569 )
Microscopy, Fluorescence, Multiphoton ( D036641 )
Calcium Signaling ( D020013 )
Time-Lapse Imaging ( D059008 )
Axons ( D001369 )
rhoA GTP-Binding Protein ( D020742 )
Fluorescence Resonance Energy Transfer ( D031541 )
rac1 GTP-Binding Protein ( D020830 )
Cerebral Cortex ( D002540 )
Cytoplasm ( D003593 )

Imaging Method

Method involved in biological imaging
confocal microscopy ( FBbi:00000251 )
two-photon laser scanning microscopy ( FBbi:00000254 )
time lapse microscopy ( FBbi:00000249 )
FRET ( FBbi:00000367 )

Paper DOI / Paper URL

People
Contact
Takeshi Imai
Kyushu University
Graduate School of Medical Sciences
-
-
Imaging dataset contributor
Satoshi Fujimoto (Kyushu University)
Marcus N Leiwe (Kyushu University)
Shuhei Aihara (Kyushu University)
Quantitative dataset contributor
-

Image datasets
461
Quantitative datasets
0

Dataset List

Thumbnail
Dataset
Organism
Kind / Links
Z-series images of P1 mouse olfactory bulb, in which mitral cell and glomeruli were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell and glomeruli were labeled
Z-series images of P6 mouse olfactory bulb, in which mitral cell and glomeruli were labeled
Z-series images of P1 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled
Z-series images of P6 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled
Z-series images of P10 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P10 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P3 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P3 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P6 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P6 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P10 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P10 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P10 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P10 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P10 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P10 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P10 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P28 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P28 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P28 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P28 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P28 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P28 mouse olfactory bulb without overexpression of Kir2.2
Z-series images of P28 mouse olfactory bulb without overexpression of Kir2.3
Z-series images of P3 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P3 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P3 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P3 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P3 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P3 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P6 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P6 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P6 mouse olfactory bulb with overexpression of Kir2.1
Z-series images of P6 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P6 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P6 mouse olfactory bulb without overexpression of Kir2.1
Z-series images of P14 mouse olfactory bulb with expression of TeNT in OSNs
Z-series images of P14 mouse olfactory bulb with expression of TeNT in OSNs
Z-series images of P14 mouse olfactory bulb with expression of TeNT in OSNs
Z-series images of P14 mouse olfactory bulb without expression of TeNT in OSNs
Z-series images of P14 mouse olfactory bulb without expression of TeNT in OSNs
Z-series images of P14 mouse olfactory bulb without expression of TeNT in OSNs
Z-series images of P6 mouse olfactory bulb with expression of TeNT in OSNs
Z-series images of P6 mouse olfactory bulb with expression of TeNT in OSNs
Z-series images of P6 mouse olfactory bulb with expression of TeNT in OSNs
Z-series images of P6 mouse olfactory bulb without expression of TeNT in OSNs
Z-series images of P6 mouse olfactory bulb without expression of TeNT in OSNs
Z-series images of P6 mouse olfactory bulb without expression of TeNT in OSNs
Z-series images of P6 mouse olfactory bulb with expression of TeNT in OSNs, which received hand rearing
Z-series images of P6 mouse olfactory bulb with expression of TeNT in OSNs, which received hand rearing
Z-series images of P6 mouse olfactory bulb with expression of TeNT in OSNs, which received hand rearing
Z-series images of P6 mouse olfactory bulb without expression of TeNT in OSNs, which received hand rearing
Z-series images of P6 mouse olfactory bulb without expression of TeNT in OSNs, which received hand rearing
Z-series images of P6 mouse olfactory bulb without expression of TeNT in OSNs, which received hand rearing
Time-lapse calcium imaging of olfactory bulb of P4 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P4 mouse in vivo expressing GCaMP3 in OSNs
Time-lapse calcium imaging of olfactory bulb of P2 mouse in vivo expressing GCaMP6f in mitral/tufted cells, after naris occusion
Time-lapse calcium imaging of olfactory bulb of P2 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice from P2 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice from P6 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice after TTX treatment from P2 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice before TTX treatment from P2 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with TTX treatment from P2 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with TTX treatment from P2 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with AP5 and CBQX treatment from P2-3 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with AP5 and CBQX treatment from P2-3 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with AP5 and CBQX treatment from P2-3 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with AP5 and CBQX treatment from P2-3 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with carbenoxolone treatment from P2-3 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with carbenoxolone treatment from P2-3 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with carbenoxolone treatment from P2-3 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with carbenoxolone treatment from P2-3 mouse expressing GCaMP3 in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Z-series images of P14 mouse olfactory bulb with expression of TeNT in mitral cells
Z-series images of P14 mouse olfactory bulb with expression of TeNT in mitral cells
Z-series images of P14 mouse olfactory bulb without expression of TeNT in mitral cells
Z-series images of P14 mouse olfactory bulb without expression of TeNT in mitral cells
Z-series images of P6 mouse olfactory bulb with expression of TeNT in mitral cells
Z-series images of P6 mouse olfactory bulb with expression of TeNT in mitral cells
Z-series images of P6 mouse olfactory bulb with expression of TeNT in mitral cells
Z-series images of P6 mouse olfactory bulb without expression of TeNT in mitral cells
Z-series images of P6 mouse olfactory bulb without expression of TeNT in mitral cells
Z-series images of P6 mouse olfactory bulb without expression of TeNT in mitral cells
Z-series images of Grin1 conditional knockout mouse brain at P14 in which mitral cells were labed by tdTomato
Z-series images of Grin1 conditional knockout mouse brain at P14 in which mitral cells were labed by tdTomato
Z-series images of Grin1 conditional knockout mouse brain at P14 in which mitral cells were labed by tdTomato
Z-series images of P14 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P14 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P14 mouse brain in which mitral cells were labed by tdTomato
Z-series images of Grin1 conditional knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1 conditional knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1 conditional knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of RhoABC knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of RhoABC knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of RhoABC knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of RhoABC-knockout and RhoA-rescued mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of RhoABC-knockout and RhoA-rescued mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of RhoABC-knockout and RhoA-rescued mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of Grin1 knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1 knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1-knockout and RhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1-knockout and RhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1-knockout and RhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1- and RhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1- and RhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1- and RhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1- and caRhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1- and caRhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Kir2.1- and caRhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX and AP5
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX and AP5
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX and AP5
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX and AP5
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX and AP5
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX and AP5
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX and AP5
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of RhoA activity in mitral cells after KCl stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of RhoA activity in mitral cells after NMDA stimulation using the mutDORA-RhoA in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after KCl stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after KCl stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after KCl stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after KCl stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after KCl stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after KCl stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 100uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 10uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 1uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 20uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 40uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells after 50uM NMDA stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 100uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 100uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 100uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 100uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 100uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 100uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 10uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 10uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 10uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 10uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 10uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 10uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 1uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 1uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 1uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 1uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 1uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 1uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 20uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 20uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 20uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 20uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 20uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 40uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 40uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 40uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 40uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 40uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 40uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 50uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 50uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 50uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 50uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 50uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of Rac1 activity in mitral cells after 50uM NMDA stimulation using the RaichuEV-Rac1 biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
FRET imaging of RhoA activity in mitral cells upon NMDAR stimulation using the DORA-RhoA biosensor in the presence of TTX
Z-series images of the barrel cortex of Grin1-KO mouse at P14 in which layer 4 neurons were labeled
Z-series images of the barrel cortex of Grin1-KO mouse at P14 in which layer 4 neurons were labeled
Z-series images of the barrel cortex of Grin1-KO and RhoA-overexpressed mouse at P14 in which layer 4 neurons were labeled
Z-series images of the barrel cortex of Grin1-KO and RhoA-overexpressed mouse at P14 in which layer 4 neurons were labeled
Z-series images of the barrel cortex of Grin1-KO and RhoA-overexpressed mouse at P14 in which layer 4 neurons were labeled
Z-series images of RhoABC knockout mouse brain at P14 in which layer 4 neurons were labed
Z-series images of RhoABC knockout mouse brain at P14 in which layer 4 neurons were labed
Z-series images of the barrel cortex of P14 mouse in which layer 4 neurons were labeled
Z-series images of the barrel cortex of P14 mouse in which layer 4 neurons were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P4 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P4 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P4 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P5 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P5 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P5 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P5 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P6 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P6 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P6 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P4 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P4 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P4 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P5 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P5 mouse olfactory bulb, in which mitral cell were labeled
Z-series images of P5 mouse olfactory bulb, in which mitral cell were labeled
Z-series images showing the expression of FLAG-Kir2.1 in tdTomato-labeled mitral cells
Z-series images of Kir2.1-overexpressing mitral cells and glutamatergic synapses in P6 mouse olfactory bulb
Z-series images of mouse olfactory bulb with overexpression of mutant-Kir2.1 in mitral cells
Z-series images of mouse olfactory bulb with overexpression of mutant-Kir2.1 in mitral cells
Z-series images of mouse olfactory bulb with overexpression of mutant-Kir2.1 in mitral cells
Z-series images of mouse olfactory bulb with overexpression of Kir2.1 in mitral cells
Z-series images of mouse olfactory bulb with overexpression of Kir2.1 in mitral cells
Z-series images of mouse olfactory bulb without overexpression of Kir2.1 in mitral cells
Z-series images of mouse olfactory bulb without overexpression of Kir2.1 in mitral cells
Z-series images mitral cells in P6 mouse olfactory bulb without naris occlusion
Z-series images mitral cells in P6 mouse olfactory bulb without naris occlusion
Z-series images mitral cells in P6 mouse olfactory bulb with naris occlusion
Z-series images mitral cells in P6 mouse olfactory bulb with naris occlusion
Z-series images of CNGA2 mutant mouse brain in which mitral cells were labed by tdTomato
Z-series images of CNGA2 mutant mouse brain in which mitral cells were labed by tdTomato
Z-series images of P14 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P14 mouse brain in which mitral cells were labed by tdTomato
Z-series images of CNGA2 mutant mouse brain in which mitral cells were labed by tdTomato
Z-series images of CNGA2 mutant mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of OSN-TeNT in the olfactory sensory neurons.
Z-series images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse images of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of OSN-TeNT in the olfactory sensory neurons.
Time-lapse calcium imaging of olfactory bulb of P5 mouse in vivo expressing GCaMP3 in mitral/tufted cells
Calcium imaging of maternally-reared OSN-TeNT mouse crossed with M/T-GCaMP6f mouse
Time-lapse calcium imaging of olfactory bulb of anesthetized mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of anesthetized mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of anesthetized mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P1 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P1 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P2 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P2 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P2 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P2 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P3 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P3 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P3 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P4 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P4 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P5 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P5 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P5 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells
High-speed calcium imaging of olfactory bulb slices using GCaMP6f
Time-lapse calcium imaging of olfactory bulb slice with AP5 treatment from P2-3 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with AP5 treatment from P2-3 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with AP5 treatment from P2-3 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with CNQX treatment from P2-3 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with CNQX treatment from P2-3 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with CNQX treatment from P2-3 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with Octanol treatment from P2 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with Octanol treatment from P2 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with Octanol treatment from P2 mouse expressing GCaMP6f in mitral/tufted cells
Time-lapse calcium imaging of olfactory bulb slice with GABA treatment from P2 mouse expressing GCaMP6f in mitral/tufted cells
Z-series images of P6 NKCC1 homozygous KO mouse brain at P6 in which mitral cells were labed by tdTomato.
Z-series images of P6 NKCC1 homozygous KO mouse brain at P6 in which mitral cells were labed by tdTomato.
Z-series images of P6 NKCC1 homozygous KO mouse brain at P6 in which mitral cells were labed by tdTomato.
Z-series images of P6 NKCC! heterozygous knockout mouse brain in which mitral cells were labed by tdTomato.
Z-series images of P6 NKCC! heterozygous knockout mouse brain in which mitral cells were labed by tdTomato.
Z-series images of P6 NKCC! heterozygous knockout mouse brain in which mitral cells were labed by tdTomato.
Z-series images of VAMP2 immunostaining in P6 mouse olfactory bulb expressing TeNT in M/T cells
Z-series images of VAMP2 immunostaining in P6 mouse olfactory bulb
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells with expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Time-lapse calcium imaging of olfactory bulb of P6 mouse in vivo expressing GCaMP6f in mitral/tufted cells without expression of M/T-TeNT in the cells
Z-series images of Grin1 conditional knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1 conditional knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1 conditional knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of P6 mouse brain in which mitral cells were labed by tdTomato
Z-series images of mitral cells labed by tdTomato in which Grin1 was knocked out specifically
Z-series images of mitral cells labed by tdTomato in which Grin1 was knocked out specifically
Z-series images of mitral cells labed by tdTomato in which Grin1 was knocked out specifically
Z-series images of Grin1-expressed mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1-knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1-knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1-knockout and rescued mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1-knockout and rescued mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of Grin1-knockout and rescued mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of RhoABC knockout mouse brain at P6 in which mitral cells were labed by tdTomato
Z-series images of P3 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled
Z-series images of P3 mouse olfactory bulb, in which mitral cell and mature glutamatergic synapses were labeled