Summary of 105-Ono-ToothDev

SSBD:database
SSBD:database URL
Title
CT images of tooth movement of the natural erupted tooth and bioengineered tooth
Description
-
Relase date
2019-11-20
Updated date
-
License
CC BY
Kind
Image data based on Experiment
Number of Datasets
9 ( Image datasets: 9, Quantitative data datasets: 0 )
Size of Datasets
333.4 KB ( Image datasets: 333.4 KB, Quantitative data datasets: 0 bytes )

Organism(s)
Canis lupus familiaris
Gene symbol(s)
NA
Protein name(s)
NA

Datatype
tooth development
Molecular Function (MF)
Biological Process (BP)
odontogenesis
Cellular Component (CC)
-
Biological Imaging Method
-
XYZ Scale
XY: NA micrometer/pixel, Z:NA
T scale
-

Image Acquisition
Experiment type
Other
Microscope type
Other
Acquisition mode
BrightField
Contrast method
Darkfield
Microscope model
PLANMECA ProMax 3D Max
Detector model
-
Objective model
-
Filter set
-

Related paper(s)

Mitsuaki Ono, Masamitsu Oshima, Miho Ogawa, Wataru Sonoyama, Emilio Satoshi Hara, Yasutaka Oida, Shigehiko Shinkawa, Ryu Nakajima, Atsushi Mine, Satoru Hayano, Satoshi Fukumoto, Shohei Kasugai, Akira Yamaguchi, Takashi Tsuji, Takuo Kuboki (2017) Practical whole-tooth restoration utilizing autologous bioengineered tooth germ transplantation in a postnatal canine model., Scientific reports, Volume 7, pp. 44522

Published in 2017 Mar 16 (Electronic publication in March 16, 2017, midnight )

(Abstract) Whole-organ regeneration has great potential for the replacement of dysfunctional organs through the reconstruction of a fully functional bioengineered organ using three-dimensional cell manipulation in vitro. Recently, many basic studies of whole-tooth replacement using three-dimensional cell manipulation have been conducted in a mouse model. Further evidence of the practical application to human medicine is required to demonstrate tooth restoration by reconstructing bioengineered tooth germ using a postnatal large-animal model. Herein, we demonstrate functional tooth restoration through the autologous transplantation of bioengineered tooth germ in a postnatal canine model. The bioengineered tooth, which was reconstructed using permanent tooth germ cells, erupted into the jawbone after autologous transplantation and achieved physiological function equivalent to that of a natural tooth. This study represents a substantial advancement in whole-organ replacement therapy through the transplantation of bioengineered organ germ as a practical model for future clinical regenerative medicine.
(MeSH Terms)

Contact
Takuo Kuboki , Okayama University , Department of Oral Rehabilitation and Regenerative Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Contributors
Mitsuaki Ono, Masamitsu Oshima, Miho Ogawa, Wataru Sonoyama, Emilio Satoshi Hara, Yasutaka Oida, Shigehiko Shinkawa, Ryu Nakajima, Atsushi Mine, Satoru Hayano, Satoshi Fukumoto, Shohei Kasugai, Akira Yamaguchi, Takashi Tsuji, Takuo Kuboki


Dataset List of 105-Ono-ToothDev

#
Dataset ID
Kind
Size
4D View
SSBD:OMERO
Download BDML
Download Images
# 4396
Dataset Kind Image data
Dataset Size 65.7 KB
4D view
SSBD:OMERO
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# 4397
Dataset Kind Image data
Dataset Size 63.6 KB
4D view
SSBD:OMERO
Download BDML
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# 4398
Dataset Kind Image data
Dataset Size 43.9 KB
4D view
SSBD:OMERO
Download BDML
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# 4399
Dataset Kind Image data
Dataset Size 34.5 KB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 4400
Datast ID Supfig5_day0
Dataset Kind Image data
Dataset Size 10.8 KB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 4401
Datast ID Supfig5_day60
Dataset Kind Image data
Dataset Size 7.7 KB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 4402
Datast ID Supfig5_day120
Dataset Kind Image data
Dataset Size 10.2 KB
4D view
SSBD:OMERO
Download BDML
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# 4403
Datast ID Supfig5_day180
Dataset Kind Image data
Dataset Size 18.2 KB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 4404
Datast ID Supfig5_sagital
Dataset Kind Image data
Dataset Size 78.4 KB
4D view
SSBD:OMERO
Download BDML
Download Image data