SSBD - SSBD:database - 421-Takenouchi-AgedYoungOocyte

No thumbnail

Summary of 421-Takenouchi-AgedYoungOocyte

SSBD:database

421-Takenouchi-AgedYoungOocyte

SSBD:database URL

https://ssbd.riken.jp/database/421-Takenouchi-AgedYoungOocyte/

SSBD:repository

ssbd-repos-000421

SSBD:repository URL

https://ssbd.riken.jp/repository/421/

Title

Live chromosome identifying and tracking in mouse oocytes

Description

Meiotic errors of relatively small chromosomes in oocytes result in egg aneuploidies that cause miscarriages and congenital diseases. Unlike somatic cells, which preferentially mis-segregate larger chromosomes, aged oocytes preferentially mis-segregate smaller chromosomes through unclear processes. Here, the authors provide a comprehensive three-dimensional chromosome identifying-and-tracking dataset throughout meiosis I in live mouse oocytes. This analysis reveals a prometaphase pathway that actively moves smaller chromosomes to the inner region of the metaphase plate. In the inner region, chromosomes are pulled by stronger bipolar microtubule forces, which facilitates premature chromosome separation, a major cause of segregation errors in aged oocytes. This study reveals a spatial pathway that facilitates aneuploidy of small chromosomes preferentially in aged eggs and implicates the role of the M phase in creating a chromosome size–based spatial arrangement.

Release date

2025-12-03

Updated date

License

CC BY 4.0

Kind

Image data based on Experiment

Number of Datasets

468 ( Image datasets: 468, Quantitative data datasets: 0 )

Size of Datasets

624.7 GB ( Image datasets: 624.7 GB, Quantitative data datasets: 0 bytes )

Organism(s)

Mus musculus

Strain(s)

B6D2F1/J

Datatype

Molecular Function (MF)

Biological Process (BP)

, female meiosis chromosome segregation

Cellular Component (CC)

chromosome

Biological Imaging Method

confocal microscopy

T scale

NA, 3 minutes

Image Acquisition

Experiment type

Microscope type

Acquisition mode

Contrast method

Microscope model

Detector model

Objective model

Filter set

Dataset List of 421-Takenouchi-AgedYoungOocyte

Thumbnail

Dataset ID

Kind

Size

4D View

SSBD:OMERO

Download BDML

Download Images

Thumbnail -

# 13171

Datast ID Fig1B_Chr1Probe

Dataset Kind Image data

Dataset Size 54.3 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13172

Datast ID Fig1B_Chr2Probe

Dataset Kind Image data

Dataset Size 60.5 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13173

Datast ID Fig1B_Chr3Probe

Dataset Kind Image data

Dataset Size 55.8 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13174

Datast ID Fig1B_Chr4Probe

Dataset Kind Image data

Dataset Size 52.5 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13175

Datast ID Fig1B_Chr5Probe

Dataset Kind Image data

Dataset Size 52.5 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13176

Datast ID Fig1B_Chr6Probe

Dataset Kind Image data

Dataset Size 48.0 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13177

Datast ID Fig1B_Chr7Probe

Dataset Kind Image data

Dataset Size 46.5 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13178

Datast ID Fig1B_Chr8Probe

Dataset Kind Image data

Dataset Size 54.0 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13179

Datast ID Fig1B_Chr9Probe

Dataset Kind Image data

Dataset Size 42.0 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13180

Datast ID Fig1B_Chr10Probe

Dataset Kind Image data

Dataset Size 52.7 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13181

Datast ID Fig1B_Chr11Probe

Dataset Kind Image data

Dataset Size 66.7 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13182

Datast ID Fig1B_Chr12Probe

Dataset Kind Image data

Dataset Size 68.2 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13183

Datast ID Fig1B_Chr13Probe

Dataset Kind Image data

Dataset Size 55.8 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13184

Datast ID Fig1B_Chr14Probe

Dataset Kind Image data

Dataset Size 66.7 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13185

Datast ID Fig1B_Chr15Probe

Dataset Kind Image data

Dataset Size 60.5 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13186

Datast ID Fig1B_Chr16Probe

Dataset Kind Image data

Dataset Size 63.6 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13187

Datast ID Fig1B_Chr17Probe

Dataset Kind Image data

Dataset Size 60.5 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13188

Datast ID Fig1B_Chr18Probe

Dataset Kind Image data

Dataset Size 57.4 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13189

Datast ID Fig1B_Chr19Probe

Dataset Kind Image data

Dataset Size 58.9 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13190

Datast ID Fig1B_ChrXProbe

Dataset Kind Image data

Dataset Size 77.5 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13191

Datast ID Fig1D_Chr1and18_1

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13192

Datast ID Fig1D_Chr1and18_2

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13193

Datast ID Fig1D_Chr1and18_3

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13194

Datast ID Fig1D_Chr1and18_4

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13195

Datast ID Fig1D_Chr1and18_5

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13196

Datast ID Fig1D_Chr1and18_6

Dataset Kind Image data

Dataset Size 595.7 MB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13197

Datast ID Fig1D_Chr1and18_7

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13198

Datast ID Fig1D_Chr1and18_8

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13199

Datast ID Fig1D_Chr1and18_9

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13200

Datast ID Fig1D_Chr1and18_10

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13201

Datast ID Fig1D_Chr1and18_11

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13202

Datast ID Fig1D_Chr1and18_12

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13203

Datast ID Fig1D_Chr1and18_13

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13204

Datast ID Fig1D_Chr1and18_14

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13205

Datast ID Fig1D_Chr1and18_15

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13206

Datast ID Fig1D_Chr1and18_16

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13207

Datast ID Fig1D_Chr1and18_18

Dataset Kind Image data

Dataset Size 1.2 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13208

Datast ID Fig1D_Chr1and18_19

Dataset Kind Image data

Dataset Size 1.2 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13209

Datast ID Fig1D_Chr1and18_20

Dataset Kind Image data

Dataset Size 1.2 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13210

Datast ID Fig1D_Chr1and18_21

Dataset Kind Image data

Dataset Size 1.2 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13211

Datast ID Fig1D_Chr1and18_22

Dataset Kind Image data

Dataset Size 1.2 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13212

Datast ID Fig1D_Chr1and18_23

Dataset Kind Image data

Dataset Size 1.2 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13213

Datast ID Fig1D_Chr1and18_24

Dataset Kind Image data

Dataset Size 1.2 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13214

Datast ID Fig1D_Chr1and18_25

Dataset Kind Image data

Dataset Size 1.2 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13215

Datast ID Fig1D_Chr2and17_1

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13216

Datast ID Fig1D_Chr2and17_2

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13217

Datast ID Fig1D_Chr2and17_3

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13218

Datast ID Fig1D_Chr2and17_4

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13219

Datast ID Fig1D_Chr2and17_5

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data

Thumbnail -

# 13220

Datast ID Fig1D_Chr2and17_6

Dataset Kind Image data

Dataset Size 1.4 GB

4D view

SSBD:OMERO

Download BDML

Download Image data