Z-series images of Grin1-knockout and RhoA-overexpressed mouse brain at P6 in which mitral cells were labed by tdTomato
Description
Z-series images of Grin1 knockout mouse brain at P6 in which mitral cells were labed by tdTomato. Grin1 coding NR1, an essential subunit of NMDA receptor was knocked out by using CRISPR-Cas9 and in utero electroporation. In this experoment, CRISPR-resistant-pCAG-RhoA was also introduced by in utero electroporation.
Fujimoto S, Leiwe MN, Aihara S, Sakaguchi R, Muroyama Y, Kobayakawa R, Kobayakawa K, Saito T, Imai T. Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice. Dev Cell. 2023 Jul 24;58(14):1221-1236.e7.
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Contact
Takeshi Imai,
, Kyushu University,
, Graduate School of Medical Sciences,
, Graduate School of Medical Sciences,