Z-series images of the vascular bed after infection with mock virus
Description
Z-series images of the vascular bed after infection with mock virus. Bronchial organoids and vascular bed composed of HUVECs (Human Umbilical Vein Endothelial Cells) were co-cultured in a special 3D microfluidic device. The virus was applied to the side of bronchial organoids, but not to the vascular bed side. Channel1: ICAM1, Channel2: Alexa Fluor 647 labeled phalloidin, Channel3: DAPI, Channel4: GFP, Channel4: Differential interference image
Fujimoto K, Kameda Y, Nagano Y, Deguchi S, Yamamoto T, Krol RP, Gee P, Matsumura Y, Okamoto T, Nagao M, Takayama K, Yokokawa R. SARS-CoV-2-induced disruption of a vascular bed in a microphysiological system caused by type-I interferon from bronchial organoids. Lab Chip . 2024 Aug 6;24(16):3863-3879.
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Contact
Ryuji Yokokawa, Kazuo Takayama
, Kyoto University, Kyoto University