Detail of Fig4A_VB_After-infect_SARS


Project
SSBD:Repository
Title
Fluorescent images of the vascular bed 4days-after infection with SARS-CoV-2 virus
Description
Fluorescent images of the vascular bed 4-days after infection with SARS-CoV-2 virus. Bronchial organoids and vascular bed composed of HUVECs (Human Umbilical Vein Endothelial Cells) were co-cultured in a special 3D microfluidic device. GFP-expressing HUVECs were used to observe the morphology of vascular bed. The virus was applied to the side of bronchial organoids, but not to the vascular bed side. Nine independent images are deposited.
Release, Updated
2025-11-26
License
CC BY
Kind
Image data
File Formats
.tif
Data size
60.7 MB

Organism
Homo sapiens ( NCBI:txid9606 )
Strain(s)
-
Cell Line
-

Datatype
-
Molecular Function (MF)
Biological Process (BP)
viral process
Cellular Component (CC)
Biological Imaging Method
fluorescence microscopy ( Fbbi:00000246 )
X scale
0.47 micrometer
Y scale
0.47 micrometer
Z scale
-
T scale
-

Image Acquisition
Experiment type
-
Microscope type
-
Acquisition mode
-
Contrast method
-
Microscope model
-
Detector model
-
Objective model
-
Filter set
-

Summary of Methods
Fujimoto K, Kameda Y, Nagano Y, Deguchi S, Yamamoto T, Krol RP, Gee P, Matsumura Y, Okamoto T, Nagao M, Takayama K, Yokokawa R. SARS-CoV-2-induced disruption of a vascular bed in a microphysiological system caused by type-I interferon from bronchial organoids. Lab Chip . 2024 Aug 6;24(16):3863-3879.
Related paper(s)

Contact
Ryuji Yokokawa, Kazuo Takayama , Kyoto University, Kyoto University
Contributors

OMERO Dataset
OMERO Project
Source