Time-series images of ERK activity at the tip of an isolated lung epithelium against the compression vertical to the distal-proximal axis
Description
Time-series images of ERK activity at the tip of an isolated lung epithelium against the compression vertical to the distal-proximal axis. The authors embedded the tissue within the FGF1-containing Matrigel filled inside a polydimethyl- siloxane chamber, and uniaxially compressed it by 33% vertically to the distal-proximal axis of the lung epithelium. The images of 2 min, 10 min, 20 min and 30 min after applying compression are reposited. The image before compression is also reposited. Channel1; bright field, Channel2; CFP, Channel3; YFP
Hirashima T and Matsuda M. ERK-mediated curvature feedback regulates branching morphogenesis in lung epithelial tissue. Curr Biol. 2024 Feb 26;34(4):683-696.e6.
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Tsuyoshi Hirashima
, National University of Singapore
, Mechanobiology Institute
, Mechanobiology Institute