Detail of Fig4A_Tg
Project
SSBD:Repository
Title
In vivo bioluminescence images of transplanted E0771 tumors in HVA-transgenic mice
Description
In vivo bioluminescence images of transplanted E0771 tumors in hypoxia response element-Venus-Akaluc (HVA) transgenic (HVA-Tg) mice. Luminescence from the reporter in HVA-Tg mice allows detection of HIF activity resulting from tumor hypoxic microenvironment or inflammation. The substrate of the luciferace (AkaLumine (Aka)-HCl) was i.p. injected 10 minutes before observation. Data of three HVA-Tg mice (TgMouse1, TgMouse2, TgMouse3) are posted. The images were obtained 0 days, 8 days, 19 days, 26 days after transplantation. In the images of Day 0, Day 8 and Day 19, the leftmost mouse is a non transgenic (Non-Tg) mouse, and right three animals are HVA-Tg mice. The data of Day26 are separeted into three images.
Release, Updated
2024-12-14
License
CC BY-NC
Kind
Image data
File Formats
.TIF
Data size
11.6 MB
Organism
Mus musculus
(
NCBI:txid10090
)
Strain(s)
C57BL/6J, B6N-Tyr^{cBrd}/BrdCrCrl
Cell Line
E0771
Datatype
-
Molecular Function (MF)
Biological Process (BP)
detection of hypoxia
(
GO:0070483
)
Cellular Component (CC)
Biological Imaging Method
luminescence detection
X scale
-
Y scale
-
Z scale
-
T scale
-
Image Acquisition
Experiment type
-
Microscope type
-
Acquisition mode
-
Contrast method
-
Microscope model
-
Detector model
-
Objective model
-
Filter set
-
Summary of Methods
See details in Miyabara H, et. al. Cancer Sci. 2023 Oct;114(10):3935-3945.
Related paper(s)
Contact
Shinae Kizaka-Kondoh
, Tokyo Institute of Technology
, School of Life Science and Technology
Contributors
Hitomi Miyabara , Shigeaki Watanabe, Hitomi Watanabe, Gen Kondoh, Takahiro Kuchimaru
OMERO Project