SSBD:database

422-Asai-KinetochoreBeads

Author reviewed

Dynamics of chromosomes and artificial kinetochore beads in mouse oocytes and embryos

SSBD:downloads

Project ID

422-Asai-KinetochoreBeads

Project SID

422

Title

Dynamics of chromosomes and artificial kinetochore beads in mouse oocytes and embryos

Description

Faithful chromosome segregation requires biorientation, where the pair of kinetochores on the chromosome establish bipolar microtubule attachment. The integrity of the kinetochore, a macromolecular complex built on centromeric DNA, is required for biorientation, but components sufficient for biorientation remain unknown. The authors show that tethering the outer kinetochore heterodimer NDC80-NUF2 to the surface of apolar microbeads establishes their biorientation-like state in mouse cells. NDC80-NUF2 microbeads align at the spindle equator and self-correct alignment errors. The alignment is associated with stable bipolar microtubule attachment and is independent of the outer kinetochore proteins SPC24-SPC25, KNL1, the Mis12 complex, inner kinetochore proteins, and Aurora. Larger microbeads align more rapidly, suggesting a size-dependent biorientation mechanism.

Submission Date

2025-02-26

Opened Date

Release Date

2025-11-28

Update Date

Kind

Image datasets

License

CC BY

Project URL

Project DOI

Metadata Version

Template Version

Funding Information

RIKEN intramural grants; RIKEN Pioneering Project “Long-timescale Molecular Chronobiology” (T.S.K.); JSPS KAKENHI 23H04948, 21H02407, and 18H05549 (T.S.K.); Mitsubishi Foundation (T.S.K.).

Total

40338 files / 3.6 TB

Image datasets

zipped 181 files / 597.0 GB, raw image 20061 files / 1.2 TB, total 20242 files / 1.8 TB

Quantitative datasets

zipped 0 files / 0 bytes, raw bdml 0 files / 0 bytes, total 0 files / 0 bytes

Biosample

Organism

Mus musculus ( NCBITaxon:10090 )

Strain

B6D2F1 ( https://www.jax.or.jp/product-and-service/rm/detail/bdf1 )

Cell

oocyte ( CL:0000023 )

embryonic cell (metazoa) ( CL:0002321 )

Cell line

MeSH

Oocytes ( D018613 )

Meiosis, Chromosome Segregation

Kinetochores, Chromosomes

Embryo, Mammalian ( D018613 )

Embryo, Mammalian

Mitosis, Chromosome Segregation

Ontology

Anatomical Entity

UBERON

embryo ( UBERON:0000922 )

Biological Process

female meiosis chromosome segregation, kinetochore assembly ( GO:0051382 )

nuclear chromosome segregation, kinetochore assembly ( GO:0051382 )

Cellular Component

kinetochore, chromosome ( GO:0005694 )

Molecular Function

Medical Subject Headings

Oocytes ( D018613 )

Meiosis, Chromosome Segregation

Kinetochores, Chromosomes

Embryo, Mammalian ( D018613 )

Embryo, Mammalian

Mitosis, Chromosome Segregation

Imaging Method

Method involved in biological imaging

confocal microscopy ( FBbi:00000251 )

time lapse microscopy ( FBbi:00000249 )

Paper DOI / Paper URL

PMID: 39298589 , doi: 10.1126/science.adn5428

People

Contact

Tomoya S Kitajima

RIKEN

Center for Biosystems Dynamics Research, Laboratory for Chromosome Segregation

Imaging dataset contributor

Kohei Asai (RIKEN)

Yuanzhuo Zhou (RIKEN)

Osamu Takenouchi (RIKEN)

Quantitative dataset contributor

Image datasets

181

Quantitative datasets

Dataset List

Thumbnail

Dataset

Organism

Kind / Links

Fig1C_Chr-and-beads_1

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_10

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_11

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_12

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_13

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_14

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_2

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_3

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_4

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_5

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_6

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_7

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_8

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig1C_Chr-and-beads_9

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in an oocyte

Fig2A_metaphase_1_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_1_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_2_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_2_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_3_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_3_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_4_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_4_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_5_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_5_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_6_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_6_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_7_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_7_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_8_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_metaphase_8_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during metaphase

Fig2A_prometaphase_10_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_10_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_11_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_11_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_1_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_1_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_2_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_2_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_3_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_3_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_4_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_4_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_5_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_5_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_6_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_6_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_7_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_7_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_8_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_8_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_9_czi

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig2A_prometaphase_9_lsm

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of immunocytochemistry stained for NDC80-NUF2 beads, HURP, and DNA during prometaphase

Fig4A_Mut9A_1

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_10

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_11

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_12

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_13

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_14

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_15

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_16

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_17

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_18

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_2

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_3

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_4

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_5

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_6

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_7

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_8

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9A_9

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in an oocyte

Fig4A_Mut9D_1

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_10

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_11

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_12

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_13

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_14

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_15

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_16

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_17

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_2

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_3

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_4

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_5

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_6

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_7

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_8

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_Mut9D_9

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9D-NUF2 microbeads in an oocyte

Fig4A_WT_1

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_10

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_11

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_12

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_13

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_14

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_15

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_2

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_3

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_4

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_5

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_6

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_7

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_8

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4A_WT_9

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in an oocyte

Fig4G_Mut9A_1

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_10

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_11

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_12

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_13

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_14

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_15

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_16

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_17

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_2

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_3

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_4

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_5

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_6

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_7

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_8

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_Mut9A_9

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-9A-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_1

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_10

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_11

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_12

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_13

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_14

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_15

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_16

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_17

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_18

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_19

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_2

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_20

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_21

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_22

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_23

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_24

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_25

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_26

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_27

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_28

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_29

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_3

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_30

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_31

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_32

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_33

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_4

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_5

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_6

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_7

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_8

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

Fig4G_WT_9

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-deltaSPC-NUF2 microbeads in a monastrol-treated and washed out oocyte

FigS3C_meiosis_1

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in oocyte during meiosis II

FigS3C_meiosis_2

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of chromosomes and NDC80-NUF2 beads in oocyte during meiosis II

FigS3C_meiosis_3

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in oocyte during meiosis II

FigS3C_meiosis_4

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of chromosomes and NDC80-NUF2 beads in oocyte during meiosis II

FigS3C_meiosis_5

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in oocyte during meiosis II

FigS3C_meiosis_6

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of chromosomes and NDC80-NUF2 beads in oocytes during meiosis II

FigS3C_meiosis_7

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of chromosomes and NDC80-NUF2 beads in oocyte during meiosis II

FigS3C_meiosis_8

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series images of chromosomes and NDC80-NUF2 beads in oocyte during meiosis II

FigS3C_mitosis_1

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_10

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_11

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_12

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_13

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_14

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_15

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_16

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_17

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_18

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_19

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_2

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_20

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_21

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_3

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_4

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_5

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_6

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_7

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_8

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis

FigS3C_mitosis_9

Mus musculus ( NCBITaxon:10090 )

Image data

Z-series and time-lapse images of chromosomes and NDC80-NUF2 beads in embryo during the first mitosis