385-Yamakoshi-thiaMichael
Author reviewedRaman images showing thia-Michael reaction in HeLa cells
Project ID
385-Yamakoshi-thiaMichael
Project SID
385
Title
Raman images showing thia-Michael reaction in HeLa cells
Description
Ratiometric Raman analysis of reversible thia-Michael reactions was achieved using alpha-cyanoacrylic acid derivatives. Among alpha-cyanoacrylic acid derivatives, the smallest derivative, ThioRas, and its glutathione adduct were simultaneously detected in various subcellular locations using Raman microscopy.
Submission Date
2024-08-26
Opened Date
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Release Date
2025-01-31
Update Date
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Kind
Image datasets
License
Project URL
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Project DOI
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Metadata Version
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Template Version
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Funding Information
This research was supported in part by a Grant-in-Aid for Scientific Research (C) (JSPS KAKENHI grant number 22K06495 to H. Y.), Drug Discovery and Life Science Research [Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)] (grant number JP22ama121040j0001 to Y. I.) from AMED, JST- CREST under Grant JPMJCR1925, JST-CREST under Grant JPMJCR2024, the Tokyo Biochemical Research Foundation, Kowa Life Science Foundation, and Photonics Center, Osaka University, Japan.
Total
12 files / 1.8 MB
Image datasets
zipped 6 files / 762.4 KB, raw image 6 files / 1.0 MB, total 12 files / 1.8 MB
Quantitative datasets
zipped 0 files / 0 bytes, raw bdml 0 files / 0 bytes, total 0 files / 0 bytes
Biosample
Organism
Homo sapiens
(
NCBITaxon:9606
)
Strain
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Cell
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Cell line
HeLa cell
(
CLO:0003684
)
MeSH
HeLa Cells
Ontology
Anatomical Entity
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UBERON
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Biological Process
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Cellular Component
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Molecular Function
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Medical Subject Headings
HeLa Cells
Imaging Method
Method involved in biological imaging
inelastic scattering of photons (Raman scattering)
(
FBbi:00000589
)
Paper DOI / Paper URL
People
Contact
Hiroyuki Yamakoshi
Tohoku University
Graduate School of Pharmaceutical Sciences
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Imaging dataset contributor
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Quantitative dataset contributor
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Image datasets
6
Quantitative datasets
0
Dataset List
Thumbnail
Dataset
Organism
Kind / Links
Raman images of cytochrome C in HeLa cells treated with alpha-cyanoacrylic acid 1a
Raman images of lipid in HeLa cells treated with alpha-cyanoacrylic acid 1a
Raman images of alpha-cyanoacrylic acid 1a in HeLa cells treated with alpha-cyanoacrylic acid 1a
Raman images of cytochrome C in HeLa cells treated with ThioRas
Raman images of lipid in HeLa cells treated with ThioRas
Raman images of ThioRas in HeLa cells treated with ThioRas