189-Kobayashi-NSCsDyn thumbnail

189-Kobayashi-NSCsDyn

Author reviewed
Confocal microscopy images of lysosomes situation in NSCs in both the DG and SVZ of mice.
Project ID
189-Kobayashi-NSCsDyn
Title
Confocal microscopy images of lysosomes situation in NSCs in both the DG and SVZ of mice.
Description
-
Release Date
2022-03-31
Update Date
-
License
Version
1.0.0
Method Summary
See details in Kobayashi T, et. al. (2019) Nat Commun., 10(1):5446.
Paper DOI
Paper URL
Kind
Image data
Total
44 files / 9.8 GB
Image datasets
zipped 17 files / 3.0 GB, raw image 27 files / 6.8 GB, total 44 files / 9.8 GB
Quantitative datasets
zipped 0 files / 0 bytes, raw bdml 0 files / 0 bytes, total 0 files / 0 bytes

Organism
Mus musculus ( NCBITaxon:10090 )
Strain
-
Cell line
-
Biological Process
negative regulation of lysosomal protein catabolic process ( GO:1905166 )
cell division ( GO:0051301)
Cellular Component
lysosome ( GO:0005764 )
Medical Subject Headings
Adult Stem Cells ( MeSH:D053687 )
Adult Stem Cells/metabolism ( MeSH:Q000378 )
Animals ( MeSH:D000818 )
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors ( MeSH:D051778 )
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics ( MeSH:Q000235 )
Dentate Gyrus ( MeSH:D018891 )
Dentate Gyrus/metabolism ( MeSH:Q000378 )
Endosomes ( MeSH:D011992 )
Endosomes/metabolism ( MeSH:Q000378 )
ErbB Receptors ( MeSH:D066246 )
ErbB Receptors/metabolism ( MeSH:Q000378 )
Lysosomes ( MeSH:D008247 )
Lysosomes/metabolism ( MeSH:Q000378 )
Mice ( MeSH:D051379 )
Mice
Knockout ( MeSH:D018345 )
Neural Stem Cells ( MeSH:D058953 )
Neural Stem Cells/metabolism ( MeSH:Q000378 )
Proteolysis ( MeSH:D059748 )
Proteostasis ( MeSH:D000074702 )
Receptors
Notch ( MeSH:D051880 )
Notch/metabolism ( MeSH:Q000378 )
Method involved in biological imaging
confocal microscopy ( FBbi:00000251 )

Image datasets
17
Quantitative datasets
0

Paper DOI / Paper URL

OMERO.gallery
OMERO
downloads

People
Contact
Taeko Kobayashi
Kyoto University
Institute for Frontier Life and Medical Sciences
-
Shogoin-Kawahara, Sakyo-ku, Kyoto 606-8507 Japan
Ryoichiro Kageyama
Kyoto University
Institute for Frontier Life and Medical Sciences
-
Shogoin-Kawahara, Sakyo-ku, Kyoto 606-8508 Japan
Imaging dataset contributor
-
Quantitative dataset contributor
-

Datasets

Thumbnail
Dataset
Organism
Kind / Links
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the SVZ in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the SVZ in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the SVZ in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 6-month-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 6-month-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 6-month-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Live-cell imaging of NSCs expressing wild type of TFEB-GFP.
Live-cell imaging of NSCs expressing S210A mutant caTFEB-GFP.