189-Kobayashi-NSCsDyn
Author reviewedConfocal microscopy images of lysosomes situation in NSCs in both the DG and SVZ of mice.
Project ID
189-Kobayashi-NSCsDyn
Title
Confocal microscopy images of lysosomes situation in NSCs in both the DG and SVZ of mice.
Description
-
Release Date
2022-03-31
Update Date
-
License
Version
1.0.0
Method Summary
See details in Kobayashi T, et. al. (2019) Nat Commun., 10(1):5446.
Kind
Image data
Total
44 files / 9.8 GB
Image datasets
zipped 17 files / 3.0 GB, raw image 27 files / 6.8 GB, total 44 files / 9.8 GB
Quantitative datasets
zipped 0 files / 0 bytes, raw bdml 0 files / 0 bytes, total 0 files / 0 bytes
Organism
Mus musculus
(
NCBITaxon:10090
)
Strain
-
Cell line
-
Biological Process
negative regulation of lysosomal protein catabolic process
(
GO:1905166
)
cell division ( GO:0051301)
Cellular Component
lysosome
(
GO:0005764
)
Medical Subject Headings
Adult Stem Cells
(
MeSH:D053687
)
Adult Stem Cells/metabolism
(
MeSH:Q000378
)
Animals
(
MeSH:D000818
)
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
(
MeSH:D051778
)
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics
(
MeSH:Q000235
)
Dentate Gyrus
(
MeSH:D018891
)
Dentate Gyrus/metabolism
(
MeSH:Q000378
)
Endosomes
(
MeSH:D011992
)
Endosomes/metabolism
(
MeSH:Q000378
)
ErbB Receptors
(
MeSH:D066246
)
ErbB Receptors/metabolism
(
MeSH:Q000378
)
Lysosomes
(
MeSH:D008247
)
Lysosomes/metabolism
(
MeSH:Q000378
)
Mice
(
MeSH:D051379
)
Mice
Knockout
(
MeSH:D018345
)
Neural Stem Cells
(
MeSH:D058953
)
Neural Stem Cells/metabolism
(
MeSH:Q000378
)
Proteolysis
(
MeSH:D059748
)
Proteostasis
(
MeSH:D000074702
)
Receptors
Notch
(
MeSH:D051880
)
Notch/metabolism
(
MeSH:Q000378
)
Method involved in biological imaging
confocal microscopy
(
FBbi:00000251
)
Image datasets
17
Quantitative datasets
0
Paper DOI / Paper URL
OMERO.gallery
People
Contact
Taeko Kobayashi
Kyoto University
Institute for Frontier Life and Medical Sciences
-
Shogoin-Kawahara, Sakyo-ku, Kyoto 606-8507 Japan
Ryoichiro Kageyama
Kyoto University
Institute for Frontier Life and Medical Sciences
-
Shogoin-Kawahara, Sakyo-ku, Kyoto 606-8508 Japan
Imaging dataset contributor
-
Quantitative dataset contributor
-
Datasets
Thumbnail
Dataset
Organism
Kind / Links
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the SVZ in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the SVZ in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the SVZ in 2-week-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 6-month-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 6-month-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Immunohistochemistry images of Lamp1, cathepsin B (CtsB), and cathepsin L (CtsL) in the DG in 6-month-old GFAP-GFP;Nestin-NLS-mCherry C57BL/6JJcl Tg mice.
Live-cell imaging of NSCs expressing wild type of TFEB-GFP.
Live-cell imaging of NSCs expressing S210A mutant caTFEB-GFP.