Summary of 234-Kobayashi-ChemotaxisDyn

SSBD:database
SSBD:database URL
Title
Time-sereis images and BDML file for quantitative information about chemotaxis behavior of N. humilis treated with or without platytocin.
Description
-
Relase date
2022-11-23
Updated date
-
License
CC BY
Kind
Image data based on Experiment
Number of Datasets
6 ( Image datasets: 6, Quantitative data datasets: 0 )
Size of Datasets
3.4 GB ( Image datasets: 3.4 GB, Quantitative data datasets: 0 bytes )

Organism(s)
Notocomplana humilis
Gene symbol(s)
NA
Protein name(s)
NA

Datatype
-
Molecular Function (MF)
Biological Process (BP)
chemotaxis
Cellular Component (CC)
Biological Imaging Method
HDR-CX680/W video recorder
X scale
0.159 millimeter per pixel
Y scale
0.159 millimeter per pixel
Z scale
-
T scale
5 seconds per time interval

Image Acquisition
Experiment type
-
Microscope type
-
Acquisition mode
-
Contrast method
-
Microscope model
-
Detector model
-
Objective model
-
Filter set
-

Related paper(s)

Aoshi Kobayashi, Mayuko Hamada, Masa-Aki Yoshida, Yasuhisa Kobayashi, Naoaki Tsutsui, Toshio Sekiguchi, Yuta Matsukawa, Sho Maejima, Joseph J Gingell, Shoko Sekiguchi, Ayumu Hamamoto, Debbie L Hay, John F Morris, Tatsuya Sakamoto, Hirotaka Sakamoto (2022) Vasopressin-oxytocin-type signaling is ancient and has a conserved water homeostasis role in euryhaline marine planarians., Science advances, Volume 8, Number 9, pp. eabk0331

Published in 2022 Mar 4 (Electronic publication in March 4, 2022, midnight )

(Abstract) Vasopressin/oxytocin (VP/OT)-related peptides are essential for mammalian antidiuresis, sociosexual behavior, and reproduction. However, the evolutionary origin of this peptide system is still uncertain. Here, we identify orthologous genes to those for VP/OT in Platyhelminthes, intertidal planarians that have a simple bilaterian body structure but lack a coelom and body-fluid circulatory system. We report a comprehensive characterization of the neuropeptide derived from this VP/OT-type gene, identifying its functional receptor, and name it the "platytocin" system. Our experiments with these euryhaline planarians, living where environmental salinities fluctuate due to evaporation and rainfall, suggest that platytocin functions as an "antidiuretic hormone" and also organizes diverse actions including reproduction and chemosensory-associated behavior. We propose that bilaterians acquired physiological adaptations to amphibious lives by such regulation of the body fluids. This neuropeptide-secreting system clearly became indispensable for life even without the development of a vascular circulatory system or relevant synapses.

Contact
Hirotaka Sakamoto , Okayama University , Graduate School of Natural Science and Tech- nology , Ushimado Marine Institute (UMI)
Contributors
Aoshi Kobayashi


Dataset List of 234-Kobayashi-ChemotaxisDyn

#
Dataset ID
Kind
Size
4D View
SSBD:OMERO
Download BDML
Download Images
# 8771
Datast ID Fig4B_ASW_post
Dataset Kind Image data
Dataset Size 654.7 MB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 8772
Datast ID Fig4B_ASW_pre
Dataset Kind Image data
Dataset Size 629.5 MB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 8773
Dataset Kind Image data
Dataset Size 541.6 MB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 8774
Datast ID Fig4B_PT_10-5M_pre
Dataset Kind Image data
Dataset Size 538.3 MB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 8775
Dataset Kind Image data
Dataset Size 537.3 MB
4D view
SSBD:OMERO
Download BDML
Download Image data

# 8776
Datast ID Fig4B_PT_10-7M_pre
Dataset Kind Image data
Dataset Size 531.9 MB
4D view
SSBD:OMERO
Download BDML
Download Image data