SSBD:repository

Summary of ssbd-repos-000222

SSBD:database

222-Dodo-RamanImaging

URL

https://ssbd.riken.jp/database/222/

Name

ssbd-repos-000222

URL

https://ssbd.riken.jp/repository/222/

DOI

https://doi.org/10.24631/ssbd.repos.2022.02.222

Title

Raman imaging in WI-38/VA-13 cells treated with 100 µM all-D-GLA

Description

Raman imaging to observe intracellular localization of GLA for analyzing the mechanism of its tumor-selective cytotoxicity

Submited Date

2022-02-16

Release Date

2022-03-09

Updated Date

License

CC BY-NC 4.0

Funding information

File formats

bmp

Data size

4.7 MB

Organism

H. sapiens

Strain

WI-38 cell (Human lung fibroblast), VA-13 cell (SV40-transformed WI-38)

Cell Line

Genes

Proteins

GO Molecular Function (MF)

tumor-selective cytotoxicity

GO Biological Process (BP)

GLA localization

GO Cellular Component (CC)

lipid droplets, lipids

Study Type

mechanistic studies

Imaging Methods

Spontaneous Raman microscopy

Method Summary

Dodo K, Sato A, Tamura Y, Egoshi S, Fujiwara K, Oonuma K, Nakao S, Terayama N, Sodeoka M. Synthesis of deuterated γ-linolenic acid and application for biological studies: metabolic tuning and Raman imaging. Chem Commun (Camb). 2021 Mar 1;57(17):2180-2183. doi: 10.1039/d0cc07824g. PMID: 33527102.