SSBD:repository

Summary of ssbd-repos-000221

Name

ssbd-repos-000221

URL

https://ssbd.riken.jp/repository/221/

DOI

https://doi.org/10.24631/ssbd.repos.2021.12.221

Title

Imaging data sets of ATDC5 cells and fetal growth plates

Description

Cross-talk between cGMP and cAMP signaling in endochondral bone formation and the physiological role of the CNP/GC-B system were demonstrated using ATDC5 cells and fetal growth plates expressing cGMP, PKA, or Ca2+ biosensors.

Submited Date

2021-12-20

Release Date

2022-01-31

Updated Date

License

CC BY-NC-SA 4.0

Funding information

File formats

oif, tif

Data size

28.8 GB

Organism

Mus musculus

Strain

Cell Line

ATDC5 cell

Genes

Proteins

GO Molecular Function (MF)

GO Biological Process (BP)

GO Cellular Component (CC)

Study Type

Förster Resonance Energy Transfer

Imaging Methods

Confocal microscopy, Two-photon microscopy

Method Summary

See details in Hirota K, Hirashima T, Horikawa K, Yasoda A, Matsuda M. C-type natriuretic peptide-induced PKA activation promotes endochondral bone formation in hypertrophic chondrocytes. Endocrinology. 2022 Jan 18:bqac005. doi: 10.1210/endocr/bqac005. Epub ahead of print. PMID: 35041746.