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Figure 1
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Figure 1b
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Figure 1c
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Figure 1d
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Figure 2
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FIgure 2a
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Figure 2b
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Figure 2c
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Figure 2d
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Figure 2e
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Figure 3
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FIgure 3a
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Figure 3b
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Figure 3c
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Figure 3e
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Figure 4
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FIgure 4g
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Figure 4b
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Figure 4c
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Figure 4d
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Figure 4e
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Figure 4h
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Figure 4i
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Figure 4j
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Figure 4k
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Figure 4l
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Figure 5
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Figure 5b
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Figure 5c
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Figure 5d
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Figure 5e
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Figure 5f
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Figure 5g
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Figure 5h
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Figure 5i
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Figure 5j
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Figure 5k
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Supplementary Figure 1
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Supplementary Figure 2
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Supplementary Figure 2a
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Supplementary Figure 2b
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Supplementary Figure 2c
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Supplementary Figure 3
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Supplementary Figure 3a
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Supplementary Figure 3b
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Supplementary Figure 4
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Supplementary Figure 5
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Supplementary Figure 6
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Supplementary Figure 7
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Supplementary Figure 8
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Supplementary Figure 9