317-Narita-Argonaute2Aggrigate
Author reviewedAggregates formation of Drosophila melanogaster Argonaute2 N-terminal region
Project ID
317-Narita-Argonaute2Aggrigate
Title
Aggregates formation of Drosophila melanogaster Argonaute2 N-terminal region
Description
Argonaute proteins play a central role in RNA silencing by forming protein-small RNA complexes responsible for the silencing process. While most Argonaute proteins have a short N-terminal region, Argonaute2
in Drosophila melanogaster (DmAgo2) harbors a long and unique N-terminal region. The N-terminal region is highly rich in glutamine and glycine residues, which is a well-known property for prion-like domains, a subclass of amyloid-forming peptides. Therefore, the possibility of the N-terminal region func- tioning as an amyloid was tested.
Release Date
2024-12-23
Update Date
-
License
Version
1.0.0
Method Summary
See details in Narita H, et. al. BMC Biol. 2023 Apr 19;21(1):78.
Kind
Image data
Total
4723 files / 70.3 GB
Image datasets
zipped 62 files / 20.2 GB, raw image 4661 files / 50.1 GB, total 4723 files / 70.3 GB
Quantitative datasets
zipped 0 files / 0 bytes, raw bdml 0 files / 0 bytes, total 0 files / 0 bytes
Organism
Drosophila
(
NCBITaxon:7215
)
Strain
-
Cell line
-
Biological Process
protein-containing complex assembly
(
GO:0065003
)
Cellular Component
-
Medical Subject Headings
-
Method involved in biological imaging
fluorescence microscopy
(
FBbi:00000246
)
time lapse microscopy
(
FBbi:00000249
)
Image datasets
52
Quantitative datasets
0
Paper DOI / Paper URL
OMERO.gallery
People
Contact
Tomohiro Shima
University of Tokyo
Department of Biological Sciences, Graduate School of Science
-
-
Sotaro Uemura
University of Tokyo
Department of Biological Sciences, Graduate School of Science
-
-
Imaging dataset contributor
Haruka Narita
(University of Tokyo)
Quantitative dataset contributor
-
Datasets
Thumbnail
Dataset
Organism
Kind / Links
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the presence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.
Fluorescence images of thioflavin-T with mCherry-Nter (N-terminal region of Argonaute2) in the absence of seeds of Nter aggregates.