Summary of 101-Oshima-ToothBioImplant

SSBD:database
SSBD:database URL
Title
SEM images of natrual tooth or bio-hybrid implant tooth surface and periodontal tissue structure
Description
-
Relase date
2019-11-20
Updated date
-
License
CC BY
Kind
Image data based on Experiment
Number of Datasets
8 ( Image datasets: 8, Quantitative data datasets: 0 )
Size of Datasets
8.0 MB ( Image datasets: 8.0 MB, Quantitative data datasets: 0 bytes )

Organism(s)
M. musculus

Datatype
tissue structure
Molecular Function (MF)
Biological Process (BP)
cementum mineralization
Cellular Component (CC)
-
Biological Imaging Method
-
XYZ Scale
XY: 0.119 micrometer/pixel, Z: NA, XY: 0.4 micrometer/pixel, Z: NA, XY: 0.066 micrometer/pixel, Z: NA
T scale
-

Image Acquisition
Experiment type
Other
Microscope type
Other
Acquisition mode
BrightField
Contrast method
Brightfield
Microscope model
-
Detector model
-
Objective model
-
Filter set
-

Related paper(s)

Masamitsu Oshima, Kaoru Inoue, Kei Nakajima, Tetsuhiko Tachikawa, Hiromichi Yamazaki, Tomohide Isobe, Ayaka Sugawara, Miho Ogawa, Chie Tanaka, Masahiro Saito, Shohei Kasugai, Teruko Takano-Yamamoto, Takashi Inoue, Katsunari Tezuka, Takuo Kuboki, Akira Yamaguchi, Takashi Tsuji (2014) Functional tooth restoration by next-generation bio-hybrid implant as a bio-hybrid artificial organ replacement therapy., Scientific reports, Volume 4, pp. 6044

Published in 2014 Aug 13 (Electronic publication in Aug. 13, 2014, midnight )

(Abstract) Bio-hybrid artificial organs are an attractive concept to restore organ function through precise biological cooperation with surrounding tissues in vivo. However, in bio-hybrid artificial organs, an artificial organ with fibrous connective tissues, including muscles, tendons and ligaments, has not been developed. Here, we have enveloped with embryonic dental follicle tissue around a HA-coated dental implant, and transplanted into the lower first molar region of a murine tooth-loss model. We successfully developed a novel fibrous connected tooth implant using a HA-coated dental implant and dental follicle stem cells as a bio-hybrid organ. This bio-hybrid implant restored physiological functions, including bone remodelling, regeneration of severe bone-defect and responsiveness to noxious stimuli, through regeneration with periodontal tissues, such as periodontal ligament and cementum. Thus, this study represents the potential for a next-generation bio-hybrid implant for tooth loss as a future bio-hybrid artificial organ replacement therapy.
(MeSH Terms)

Contact
Takashi Tsuji , Tokyo University of Science , Research Institute for Science and Technology
Contributors
Masamitsu Oshima, Kaoru Inoue, Kei Nakajima, Tetsuhiko Tachikawa, Hiromichi Yamazaki, Tomohide Isobe, Ayaka Sugawara, Miho Ogawa, Chie Tanaka, Masahiro Saito, Shohei Kasugai, Teruko Takano-Yamamoto, Takashi Inoue, Katsunari Tezuka, Takuo Kuboki, Akira Yamaguchi, Takashi Tsuji


Dataset List of 101-Oshima-ToothBioImplant

#
Dataset ID
Kind
Size
4D View
SSBD:OMERO
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# 4353
Datast ID fig1d_HAImplant
Dataset Kind Image data
Dataset Size 1020.0 KB
4D view
SSBD:OMERO
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# 4354
Dataset Kind Image data
Dataset Size 1020.0 KB
4D view
SSBD:OMERO
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# 4355
Dataset Kind Image data
Dataset Size 1020.0 KB
4D view
SSBD:OMERO
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# 4356
Dataset Kind Image data
Dataset Size 1020.0 KB
4D view
SSBD:OMERO
Download BDML
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# 4357
Datast ID fig2a_naturaltooth
Dataset Kind Image data
Dataset Size 1020.0 KB
4D view
SSBD:OMERO
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# 4358
Dataset Kind Image data
Dataset Size 1020.0 KB
4D view
SSBD:OMERO
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# 4359
Datast ID fig2a_osseoImplant
Dataset Kind Image data
Dataset Size 1020.0 KB
4D view
SSBD:OMERO
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# 4360
Dataset Kind Image data
Dataset Size 1017.6 KB
4D view
SSBD:OMERO
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Download Image data