Oocyte formation in mammals is a tightly regulated process critical for female fertility. We developed an ex vivo culture system that mimics in vivo ovarian development and enables long-term, high-resolution live imaging of mouse fetal ovaries. This dataset comprises time-lapse image sequences capturing dynamic germ cell behaviors during the transition from oogonia to nascent oocytes.
Submission date
2025-08-14
Release date
2026-04-21
Update date
-
License
CC BY license
Funding information
-
File formats
The dataset contains image files in CZI, LSM, TIFF, and JPEG formats. CZI and LSM are Zeiss microscope file formats that store multi-dimensional imaging data. TIFF and JPEG files are standard formats; TIFF images are uncompressed or losslessly compressed, whereas JPEG images are lossy compressed. Movie files are provided in AVI or MP4 formats, both using standard compression codecs.
Aizawa, Eishi, Hara, Junko, Abe, Takaya, Kitajima, Tomoya S. (2025/01/01), <em>Ex vivo</em> live imaging unveils the dynamics of oocyte formation in mice, bioRxiv, 2025.08.04.668457
Aizawa, Eishi, Shimamoto, So, Kajikawa, Eriko, Hara, Junko, Abe, Takaya, Shibuya, Hiroki, Kitajima, Tomoya S. (2026) Dynamic blebbing and absence of organelle transfer during mouse oocyte formation, The EMBO Journal