Detail of Fig6_HL-60_DAC0.5_Cera_1
Project
SSBD:Repository
Title
Time-lapse images of HL-60 cells treated with 0.5 micromolar DAC and ceralasertib
Description
Time-lapse images of HL-60 cells treated with 0.5 micromolar Decitabine and the ATR-selective inhibitor ceralasertib. DNA was labeled with siR-DNA. Channel1; siR-DNA, Channel2; bright field
Release, Updated
2025-04-10
License
CC BY
Kind
Image data
File Formats
.tif
Data size
1.4 GB
Datatype
-
Molecular Function (MF)
Biological Process (BP)
cell division
,
cell cycle
Cellular Component (CC)
Biological Imaging Method
confocal microscopy
(
Fbbi:00000251
)
X scale
0.325 micrometer/pixel
Y scale
0.325 micrometer/pixel
Z scale
-
T scale
5 minutes
Image Acquisition
Experiment type
-
Microscope type
-
Acquisition mode
-
Contrast method
-
Microscope model
-
Detector model
-
Objective model
-
Filter set
-
Summary of Methods
Yabushita T, Chinen T, Nishiyama A, Asada S, Shimura R, Isobe T, Yamamoto K, Sato N, Enomoto Y, Tanaka Y, Fukuyama T, Satoh H, Kato K, Saitoh K, Ishikawa T, Soga T, Nannya Y, Fukagawa T, Nakanishi M, Kitagawa D, Kitamura T, Goyama S. Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment. Cell Rep. 2023 Sep 26;42(9):113098.
Related paper(s)
Contact
Susumu Goyama
, The University of Tokyo
, Division of Molecular Oncology, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences
, Division of Molecular Oncology, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences
Contributors
Tomohiro Yabushita, Takumi Chinen
OMERO Project
Source