Detail of Fig3b_inclusion_MSA_6
Project
SSBD:Repository
Title
Z-stack images of MSA seed transduction cells
Description
Z-stack images of multiple system atrophy (MSA) seed transducted HEK293 cell line stably expressing green fluorescent protein (GFP)-fused human alpha-synuclein with A53T mutation (293-SynG). The fixed cells were observed by super-resolution structured illumination microscopy (SR-SIM).
Release, Updated
2025-01-31
License
CC BY
Kind
Image data
File Formats
.tif
Data size
11.7 MB
Datatype
-
Molecular Function (MF)
Biological Process (BP)
inclusion body assembly
(
GO:0070841
)
Cellular Component (CC)
inclusion body
(
GO:0016234
)
Biological Imaging Method
X scale
264.58 micrometer
Y scale
264.58 micrometer
Z scale
3 micrometer
T scale
-
Image Acquisition
Experiment type
-
Microscope type
-
Acquisition mode
-
Contrast method
-
Microscope model
-
Detector model
-
Objective model
-
Filter set
-
Summary of Methods
Okuzumi A, Hatano T, Matsumoto G, Nojiri S, Ueno SI, Imamichi-Tatano Y, Kimura H, Kakuta S, Kondo A, Fukuhara T, Li Y, Funayama M, Saiki S, Taniguchi D, Tsunemi T, McIntyre D, Gerardy JJ, Mittelbronn M, Kruger R, Uchiyama Y, Nukina N, Hattori N. Propagative alpha-synuclein seeds as serum biomarkers for synucleinopathies. Nat Med. 2023 Jun;29(6):1448-1455.
Related paper(s)
Contact
Nobutaka Hattori
, Juntendo University
, Department of Neurology
, Department of Neurology
Contributors
Ayami Okuzumi, Soichiro Kakuta, Yasuo Uchiyama
OMERO Project