Detail of Fig2b_TEM_DLB
Project
SSBD:Repository
Title
TEM images of IP/RT-QuIC products derived from DLB patients serum
Description
TEM images of products of immunoprecipitation-based real-time quaking-induced conversion (IP/RT-QuIC) products, which enables the detection of pathogenic alpha-synuclein seeds in the serum of individuals with synucleinopathies, derived from dementia with Lewy bodies (DLB) patients serum.
Release, Updated
2025-01-31
License
CC BY
Kind
Image data
File Formats
TIFF
Data size
8.9 MB
Datatype
-
Molecular Function (MF)
Biological Process (BP)
Cellular Component (CC)
Biological Imaging Method
transmission electron microscopy
(
Fbbi:00000258
)
X scale
146.82 micrometer
Y scale
146.82 micrometer
Z scale
-
T scale
-
Image Acquisition
Experiment type
-
Microscope type
-
Acquisition mode
-
Contrast method
-
Microscope model
-
Detector model
-
Objective model
-
Filter set
-
Summary of Methods
Okuzumi A, Hatano T, Matsumoto G, Nojiri S, Ueno SI, Imamichi-Tatano Y, Kimura H, Kakuta S, Kondo A, Fukuhara T, Li Y, Funayama M, Saiki S, Taniguchi D, Tsunemi T, McIntyre D, Gerardy JJ, Mittelbronn M, Kruger R, Uchiyama Y, Nukina N, Hattori N. Propagative alpha-synuclein seeds as serum biomarkers for synucleinopathies. Nat Med. 2023 Jun;29(6):1448-1455.
Related paper(s)
Contact
Nobutaka Hattori
, Juntendo University
, Department of Neurology
, Department of Neurology
Contributors
Ayami Okuzumi, Soichiro Kakuta, Yasuo Uchiyama
OMERO Project